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Concept information

Preferred term

Endodermal Sinus Tumor  

Type

  • mesh:Descriptor

Definition

  • An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)

Broader concept

Entry terms

  • Yolk Sac Tumor

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-KPDX1QHX-F

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RDF/XML TURTLE JSON-LD Created 6/25/93, last modified 7/6/09