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Concept information

Metabolism > RNA Processing, Post-Transcriptional > RNA Splicing > Trans-Splicing
Chemical Phenomena > Biochemical Phenomena > RNA Processing, Post-Transcriptional > RNA Splicing > Trans-Splicing
Genetic Phenomena > Gene Expression Regulation > RNA Processing, Post-Transcriptional > RNA Splicing > Trans-Splicing

Preferred term

Trans-Splicing  

Type

  • mesh:Descriptor

Definition

  • The joining of RNA from two different genes. One type of trans-splicing is the "spliced leader" type (primarily found in protozoans such as trypanosomes and in lower invertebrates such as nematodes) which results in the addition of a capped, noncoding, spliced leader sequence to the 5' end of mRNAs. Another type of trans-splicing is the "discontinuous group II introns" type (found in plant/algal chloroplasts and plant mitochondria) which results in the joining of two independently transcribed coding sequences. Both are mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells are also capable of trans-splicing.

Broader concept

Related concepts

Entry terms

  • RNA Trans-Splicing
  • Trans RNA Splicing
  • Trans Splicing

Allowable Qualifier(s)

In other languages

  • Épissage en trans

    French

  • Épissage en trans des ARN
  • Épissage intermoléculaire
  • Trans-épissage
  • Trans-splicing

URI

http://data.loterre.fr/ark:/67375/JVR-KR0TGL8Z-Z

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RDF/XML TURTLE JSON-LD Created 6/11/98, last modified 7/1/16