Concept information
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Infant, Newborn, Diseases
Erythroblastosis, Fetal
...
Female Urogenital Diseases and Pregnancy Complications
Pregnancy Complications
Fetal Diseases
Erythroblastosis, Fetal
Preferred term
Kernicterus
Type
-
mesh:Descriptor
Definition
- A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
Broader concept
Entry terms
- Bilirubin Encephalopathy
- Encephalopathy, Bilirubin
- Encephalopathy, Hyperbilirubinemic
- Hyperbilirubinemic Encephalopathy
Allowable Qualifier(s)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemically induced (Qualifier)
- classification (Qualifier)
- complications (Qualifier)
- diagnosis (Qualifier)
- diagnostic imaging (Qualifier)
- diet therapy (Qualifier)
- drug therapy (Qualifier)
- economics (Qualifier)
- embryology (Qualifier)
- enzymology (Qualifier)
- epidemiology (Qualifier)
- ethnology (Qualifier)
- etiology (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- mortality (Qualifier)
- nursing (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiopathology (Qualifier)
- prevention & control (Qualifier)
- psychology (Qualifier)
- radiotherapy (Qualifier)
- rehabilitation (Qualifier)
- surgery (Qualifier)
- therapy (Qualifier)
- urine (Qualifier)
- veterinary (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Encéphalopathie bilirubinique
-
Encéphalopathie hyperbilirubinémique
-
Encéphalopathie par hyperbilirubinémie
-
Kernictère
URI
http://data.loterre.fr/ark:/67375/JVR-KR4JWLXF-Q
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