Concept information
Preferred term
Genes, myb
Type
-
mesh:Descriptor
Definition
- Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
Broader concept
Entry terms
- myb Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène myb
URI
http://data.loterre.fr/ark:/67375/JVR-KZZG7LGJ-K
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