Concept information
Preferred term
Transient Receptor Potential Channels
Type
-
mesh:Descriptor
Definition
- A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
Broader concept
Narrower concepts
Entry terms
- Transient Receptor Potential Cation Channel
- Transient Receptor Potential Cation Channels
- Transient Receptor Potential Channel
- TRP Cation Channel
- TRP Cation Channels
- TRP Membrane Proteins
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Canal à potentiel de récepteur transitoire
-
Canal cationique TRP
-
Canal TRP (Transient Receptor Potential)
-
Canaux à potentiel de récepteur transitoire
-
Canaux TRP (Transient Receptor Potential)
-
Protéines membranaires TRP
-
Protéines-canaux de type TRP
-
Récepteur-canal sélectif pour les cations
-
Récepteurs-canaux sélectifs pour les cations
URI
http://data.loterre.fr/ark:/67375/JVR-L11DW6NJ-0
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