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Concept information

Preferred term

Placenta Growth Factor  

Type

  • mesh:Descriptor

Definition

  • An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

Entry terms

  • 144589-93-5

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-L1615X39-X

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 7/5/16