Concept information
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Genome Components
Interspersed Repetitive Sequences
Retroelements
Short Interspersed Nucleotide Elements
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Repetitive Sequences, Nucleic Acid
Interspersed Repetitive Sequences
Retroelements
Short Interspersed Nucleotide Elements
Preferred term
Alu Elements
Type
-
mesh:Descriptor
Definition
- The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Broader concept
Entry terms
- Alu Family
- Alu Repetitive Sequences
Allowable Qualifier(s)
In other languages
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French
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Éléments Alu
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Famille Alu
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Séquences Alu répétées
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Séquences répétées Alu
URI
http://data.loterre.fr/ark:/67375/JVR-L366BNB0-6
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