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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2

Preferred term

Cyclin-Dependent Kinase 2  

Type

  • mesh:Descriptor

Definition

  • A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

Broader concept

Entry terms

  • Cdc2-Related Protein Kinase
  • CDK2 Protein
  • Cdk2 Protein Kinase
  • p33cdk2 Kinase

Allowable Qualifier(s)

In other languages

  • Kinase-2 cycline-dépendante

    French

  • Kinase cycline-dépendante de type 2
  • Kinase p33(cdk2)
  • Kinase-2 dépendante de cycline
  • Protéine CDK2
  • Proteine-kinase apparentée à Cdc2
  • Protéine-kinase Cdk2

URI

http://data.loterre.fr/ark:/67375/JVR-L3FDRLHQ-H

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 5/21/21