Concept information
Preferred term
Autophagy-Related Protein 7
Type
-
mesh:Descriptor
Definition
- An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
Broader concept
Entry terms
- ATG12-Activating Enzyme E1 ATG7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Enzyme ATG7 d'activation des modificateurs analogues à l'ubiquitine
-
Protéine analogue à l'enzyme E1 d'activation de l'ubiquitine
-
Protéine ATG-7
-
Protéine ATG7
-
Protéine-7 liée à l'autophagie
URI
http://data.loterre.fr/ark:/67375/JVR-L8L9Q0LX-G
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