Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Infections > Virus Diseases > Slow Virus Diseases > Subacute Sclerosing Panencephalitis

Preferred term

Subacute Sclerosing Panencephalitis  

Type

  • mesh:Descriptor

Definition

  • A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

Entry terms

  • Encephalitis, Inclusion Body, Measles
  • Inclusion Body Encephalitis, Measles
  • Leukoencephalitis, Subacute Sclerosing
  • Leukoencephalitis, Van Bogaert's
  • Measles Inclusion Body Encephalitis
  • Panencephalitis, Subacute Sclerosing
  • Sclerosing Leukoencephalitis, Subacute
  • Sclerosing Panencephalitis, Subacute
  • SSPE
  • Van Bogaert's Leukoencephalitis

In other languages

  • French

  • Encéphalite à inclusions
  • Encéphalite morbilleuse à inclusions
  • LESS
  • Leuco-encéphalite sclérosante subaiguë
  • Leuco-encéphalite sclérosante subaigüe
  • Leucoencéphalite sclérosante subaiguë
  • Maladie de Van Bogaert
  • Panencéphalite sclérosante subaiguë
  • Panencéphalite sclérosante subaigüe

URI

http://data.loterre.fr/ark:/67375/JVR-L9D5LCCL-M

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 6/30/21