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Concept information

Preferred term

Myasthenic Syndromes, Congenital  

Type

  • mesh:Descriptor

Definition

  • A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes presynaptic, synaptic, and postsynaptic disorders (that are not of autoimmune origin). The majority of these diseases are caused by mutations of various subunits of the nicotinic acetylcholine receptor (RECEPTORS, NICOTINIC) on the postsynaptic surface of the junction. (From Arch Neurol 1999 Feb;56(2):163-7)

Entry terms

  • Congenital Myasthenia
  • Congenital Myasthenia Gravis
  • Congenital Myasthenic Syndrome
  • Congenital Myasthenic Syndromes
  • Myasthenia Gravis, Congenital

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-LCCP1P97-K

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RDF/XML TURTLE JSON-LD Created 11/8/99, last modified 5/27/20