Concept information
Preferred term
Small Leucine-Rich Proteoglycans
Type
-
mesh:Descriptor
Definition
- A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS.
Broader concept
Narrower concepts
Entry terms
- SLRP Proteoglycan
- SLRP Proteoglycans
- Small Leucine Rich Proteoglycan
- Small Leucine-Rich Proteoglycan
- Small Leucine-Rich Repeat Proteoglycan
- Small Leucine-Rich Repeat Proteoglycans
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Petit protéoglycane à répétition riche en leucine
-
Petits protéoglycanes à répétition riche en leucine
-
Protéoglycanes SLRP
URI
http://data.loterre.fr/ark:/67375/JVR-LG1LW16S-J
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