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Concept information

Preferred term

Immunoglobulin Light-chain Amyloidosis  

Type

  • mesh:Descriptor

Definition

  • A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.

Entry terms

  • AL Amyloidosis
  • Amyloidosis, Immunoglobulin Light-chain
  • Amyloidosis, Primary
  • Primary Amyloidosis
  • Primary Systemic Amyloidosis

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-LHRVVLQX-W

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/20/17