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Concept information

Biological Factors > Intercellular Signaling Peptides and Proteins > EGF Family of Proteins > Epidermal Growth Factor
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > EGF Family of Proteins > Epidermal Growth Factor
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > EGF Family of Proteins > Epidermal Growth Factor
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Gastrointestinal Hormones > Epidermal Growth Factor

Preferred term

Epidermal Growth Factor  

Type

  • mesh:Descriptor

Definition

  • A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.

Broader concept

Related concepts

Entry terms

  • 62229-50-9
  • beta-Urogastrone
  • EGF
  • Epidermal growth factor
  • Epidermal Growth Factor-Urogastrone
  • Human Urinary Gastric Inhibitor
  • Urogastrone

Allowable Qualifier(s)

In other languages

  • Facteur de croissance épidermique

    French

  • 62229-50-9
  • bêta-Urogastrone
  • EGF (Epidermal Growth Factor)
  • Epidermal growth factor
  • Facteur de croissance de l'épiderme
  • HUGI
  • Human urinary gastric inhibitor
  • Urogastrone
  • Urogastrone bêta

URI

http://data.loterre.fr/ark:/67375/JVR-LJBBT1XG-M

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