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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Receptor, Fibroblast Growth Factor, Type 2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Fibroblast Growth Factor, Type 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Fibroblast Growth Factor, Type 2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, Fibroblast Growth Factor, Type 2
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Fibroblast Growth Factor > Receptor, Fibroblast Growth Factor, Type 2

Preferred term

Receptor, Fibroblast Growth Factor, Type 2  

Type

  • mesh:Descriptor

Definition

  • A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME). An isoform of fibroblast growth factor receptor 2 found mainly in EPITHELIAL CELLS that is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10.

Broader concept

Related concepts

Entry terms

  • Bek Fgf Receptor Kinase
  • BEK Fibroblast Growth Factor Receptor
  • BEK Fibroblast Growth Factor Receptor Kinase
  • BEK Protein Tyrosine Kinase
  • Bek-Related Fibroblast Growth Factor-Receptor-1
  • CD332 Antigen
  • FGFR2 Protein
  • Fibroblast Growth Factor Receptor 2
  • Fibroblast Growth Factor Receptors 2

Allowable Qualifier(s)

In other languages

  • Récepteur FGFR2

    French

  • Bek Fgf Receptor kinase
  • BEK Protein tyrosine kinase
  • Protéine FGFR2
  • Récepteur 2 du facteur de croissance fibroblastique
  • Récepteur 2 du facteur fibroblastique de croissance

URI

http://data.loterre.fr/ark:/67375/JVR-LSQB2HFM-5

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 5/21/21