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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecule-1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecule-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecule-1
Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > Cell Adhesion Molecule-1

Preferred term

Cell Adhesion Molecule-1  

Type

  • mesh:Descriptor

Definition

  • A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.

Broader concept

Related concepts

Entry terms

  • CADM1 Protein
  • IGSF4 Protein
  • TSLC1 Protein
  • Tumor Suppressor in Lung Cancer 1 Protein

Allowable Qualifier(s)

In other languages

  • Molécule-1 d'adhésion cellulaire

    French

  • Protéine CADM1
  • Protéine IGSF4
  • Protéine suppresseur de tumeur dans le cancer du poumon de type 1
  • Protéine suppresseur de tumeur dans le cancer pulmonaire de type 1
  • Protéine TSLC1

URI

http://data.loterre.fr/ark:/67375/JVR-LTHS11MW-Z

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/29/17