Concept information
Preferred term
3-Iodobenzylguanidine
Type
-
mesh:Descriptor
Definition
- A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Broader concept
Entry terms
- 35MRW7B4AD
- 74075-13-1 (125I labeled cpd)
- 76924-93-1 (123I labeled cpd)
- 77679-27-7 (3-Iodobenzylguanidine)
- Iobenguane
- meta-Iodobenzylguanidine
- MIBG
- m-Iodobenzylguanidine
- Q461L7AK4R
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
3-Iodobenzylguanidine
-
35MRW7B4AD
-
74075-13-1 (125I labeled cpd)
-
76924-93-1 (123I labeled cpd)
-
77679-27-7 (3-Iodobenzylguanidine)
-
Iobenguane
-
Q461L7AK4R
URI
http://data.loterre.fr/ark:/67375/JVR-LW773Q21-N
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