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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Certolizumab Pegol
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Certolizumab Pegol
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Polyethylene Glycols > Certolizumab Pegol
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Polyethylene Glycols > Certolizumab Pegol
Macromolecular Substances > Polymers > Polyethylene Glycols > Certolizumab Pegol
... > Organic Chemicals > Alcohols > Glycols > Ethylene Glycols > Polyethylene Glycols > Certolizumab Pegol

Preferred term

Certolizumab Pegol  

Type

  • mesh:Descriptor

Definition

  • A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.

Broader concept

Related concepts

Entry terms

  • 428863-50-7
  • UMD07X179E

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-LX9R772G-6

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RDF/XML TURTLE JSON-LD Created 7/10/15, last modified 7/1/21