Concept information
Preferred term
Desipramine
Type
-
mesh:Descriptor
Definition
- A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Broader concept
Entry terms
- 1Y58DO4MY1
- 50-47-5 (Desipramine)
- 58-28-6 (HCl)
- 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
- Demethylimipramine
- Desmethylimipramine
- TG537D343B
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
1Y58DO4MY1
-
50-47-5 (Desipramine)
-
58-28-6 (HCl)
-
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
-
TG537D343B
URI
http://data.loterre.fr/ark:/67375/JVR-LXJFNVPL-1
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