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... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Inhibitor of Apoptosis Proteins > Baculoviral IAP Repeat-Containing 3 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Inhibitor of Apoptosis Proteins > Baculoviral IAP Repeat-Containing 3 Protein
... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > Inhibitor of Apoptosis Proteins > Baculoviral IAP Repeat-Containing 3 Protein

Preferred term

Baculoviral IAP Repeat-Containing 3 Protein  

Type

  • mesh:Descriptor

Definition

  • A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.

Broader concept

Entry terms

  • Apoptosis Inhibitor 2
  • Baculoviral IAP Repeat Containing Protein 3
  • BIRC3 Protein
  • Cellular Inhibitor of Apoptosis-2
  • c-IAP2 Protein
  • cIAP2 Protein
  • Hiap-1 Protein
  • IAP1 Protein
  • Inhibitor of Apoptosis 1 Protein
  • Inhibitor of Apoptosis Protein 1

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-M1CSSN71-W

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/29/17