Concept information
Preferred term
TNF-Related Apoptosis-Inducing Ligand
Type
-
mesh:Descriptor
Definition
- A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
Broader concept
Entry terms
- Apo-2 Ligand
- Apo-2L Protein
- CD253 Antigen
- TNF Superfamily, Member 10
- TRAIL Protein
- Tumor Necrosis Factor Ligand Superfamily Member 10
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Ligand Apo-2L
-
Ligand de Apo-2
-
Ligand TNFSF10
-
Membre-10 de la superfamille des ligands TNF
-
Membre-10 de la superfamille des TNF ligands
-
Membre-10 de la superfamille du facteur de nécrose tumorale
-
Membre-10 de la superfamille du TNF
-
Protéine Apo-2L
-
Protéine TRAIL
-
TNF-related apoptosis-inducing ligand
URI
http://data.loterre.fr/ark:/67375/JVR-M2NCHWZ0-W
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