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Concept information

Preferred term

TNF-Related Apoptosis-Inducing Ligand  

Type

  • mesh:Descriptor

Definition

  • A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.

Broader concept

Entry terms

  • Apo-2 Ligand
  • Apo-2L Protein
  • CD253 Antigen
  • TNF Superfamily, Member 10
  • TRAIL Protein
  • Tumor Necrosis Factor Ligand Superfamily Member 10

In other languages

  • French

  • Ligand Apo-2L
  • Ligand de Apo-2
  • Ligand TNFSF10
  • Membre-10 de la superfamille des ligands TNF
  • Membre-10 de la superfamille des TNF ligands
  • Membre-10 de la superfamille du facteur de nécrose tumorale
  • Membre-10 de la superfamille du TNF
  • Protéine Apo-2L
  • Protéine TRAIL
  • TNF-related apoptosis-inducing ligand

URI

http://data.loterre.fr/ark:/67375/JVR-M2NCHWZ0-W

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 5/24/17