Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Musculoskeletal and Neural Physiological Phenomena > Musculoskeletal Physiological Phenomena > Bone Remodeling
Biological Phenomena > Regeneration > Bone Remodeling

Preferred term

Bone Remodeling  

Type

  • mesh:Descriptor

Definition

  • The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.

Broader concept

Narrower concepts

Entry terms

  • Bone Turnover

Allowable Qualifier(s)

In other languages

  • Remodelage osseux

    French

  • Remodelage du tissu osseux
  • Renouvellement du tissu osseux
  • Renouvellement osseux

URI

http://data.loterre.fr/ark:/67375/JVR-M3R8ZFRL-S

Download this concept:

RDF/XML TURTLE JSON-LD Created 4/29/91, last modified 6/2/16