Concept information
Preferred term
Tumor Suppressor Protein p53
Type
-
mesh:Descriptor
Definition
- Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Broader concept
Entry terms
- Cellular Tumor Antigen p53
- Oncoprotein p53
- p53 Antigen
- p53 Tumor Suppressor Protein
- pp53 Phosphoprotein
- TP53 Protein
- TRP53 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Antigène p53
-
Antigène tumoral p53
-
Oncoprotéine p53
-
Phosphoprotéine pp53
-
Protéine p53
-
Protéine suppresseur de tumeur p53
-
Protéine TP53
-
Protéine TRP53
URI
http://data.loterre.fr/ark:/67375/JVR-M53LK2T1-0
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