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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Glycoside Hydrolases > Hexosaminidases > beta-N-Acetylhexosaminidases

Preferred term

beta-N-Acetylhexosaminidases  

Type

  • mesh:Descriptor

Definition

  • A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.

Broader concept

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Related concepts

Entry terms

  • beta-Hexosaminidase
  • beta-N-Acetyl-D-hexosaminidase
  • beta-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase
  • beta-N-Acetyl-hexosaminidase
  • beta-N-Acetylhexosaminidase
  • N-Acetyl-beta-D-hexosaminidase

Allowable Qualifier(s)

In other languages

  • beta-N-Acetylhexosaminidases

    French

  • beta-Hexosaminidase
  • beta-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase
  • beta-N-Acetyl-hexosaminidase
  • beta-N-Acetylhexosaminidase
  • N-Acétyl-bêta-D-hexosaminidase

URI

http://data.loterre.fr/ark:/67375/JVR-M8NRMFCW-R

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RDF/XML TURTLE JSON-LD Created 6/2/86, last modified 7/9/07