: MeSH: Amino Acid Substitution

Genetic Phenomena > Mutagenesis > Amino Acid Substitution

Investigative Techniques > Genetic Techniques > Genetic Engineering > Protein Engineering > Amino Acid Substitution

Amino Acid Substitution

The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

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