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... > Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Proglucagon > Glucagon-Like Peptides > Glucagon-Like Peptide 1
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Gastrointestinal Hormones > Proglucagon > Glucagon-Like Peptides > Glucagon-Like Peptide 1
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pancreatic Hormones > Proglucagon > Glucagon-Like Peptides > Glucagon-Like Peptide 1
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pancreatic Hormones > Proglucagon > Glucagon-Like Peptides > Glucagon-Like Peptide 1

Preferred term

Glucagon-Like Peptide 1  

Type

  • mesh:Descriptor

Definition

  • A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.

Broader concept

Narrower concepts

Entry terms

  • 89750-14-1
  • GLP-1
  • Glucagon-Like Peptide-1

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Glucagon-like peptide 1

    French

  • 89750-14-1
  • GLP-1
  • Glucagon-like peptide I
  • Glucagon-like peptide-1
  • Proglucagon (78-107)

URI

http://data.loterre.fr/ark:/67375/JVR-MDZFXH5C-T

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 7/5/18