Concept information
Preferred term
Genes, rel
Type
-
mesh:Descriptor
Definition
- Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
Broader concept
Entry terms
- rel Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène rel
URI
http://data.loterre.fr/ark:/67375/JVR-MFL64BSS-R
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