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Concept information

Preferred term

Keratins  

Type

  • mesh:Descriptor

Definition

  • A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

Entry terms

  • 68238-35-7
  • 9008-18-8 (other number)
  • Cytokeratin
  • Keratin

In other languages

  • French

  • 68238-35-7
  • 9008-18-8 (other number)
  • Cytokératines

URI

http://data.loterre.fr/ark:/67375/JVR-MH528X6P-B

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