Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Sterol Regulatory Element Binding Proteins > Sterol Regulatory Element Binding Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Sterol Regulatory Element Binding Proteins > Sterol Regulatory Element Binding Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Sterol Regulatory Element Binding Proteins > Sterol Regulatory Element Binding Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Sterol Regulatory Element Binding Proteins > Sterol Regulatory Element Binding Protein 1

Preferred term

Sterol Regulatory Element Binding Protein 1  

Type

  • mesh:Descriptor

Definition

  • A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING. SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis. SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form in SPLEEN.

Broader concept

Entry terms

  • SRE-1 Binding Protein
  • SREBP1 Protein
  • Sterol Regulatory Element-Binding Protein 1

Allowable Qualifier(s)

In other languages

  • Protéine-1 de liaison à l'élément de régulation des stérols

    French

  • Facteur de transcription SREBP-1
  • Facteur de transcription SREBP1
  • Facteur SREBP-1
  • Facteur transcriptionnel SREBP-1
  • Facteur transcriptionnel SREBP1
  • Protéine SREBP-1
  • Protéine SREBP1
  • Protéine-1 de fixation à l'élément de régulation des stérols
  • Protéine-1 se fixant à l'élément de régulation des stérols
  • Protéine-1 se liant à l'élément de régulation des stérols

URI

http://data.loterre.fr/ark:/67375/JVR-MQ11VK15-M

Download this concept:

RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 7/17/09