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Concept information

Preferred term

NLR Proteins  

Type

  • mesh:Descriptor

Definition

  • Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

Entry terms

  • NLR Protein
  • NOD-like Receptor
  • NOD-like Receptors
  • Nucleotide-Binding Domain Leucine-Rich Repeat Protein
  • Nucleotide-binding Domain Leucine-rich Repeat Proteins

In other languages

  • French

  • Protéine NLR
  • Protéines portant un domaine liant les nucléotides et une répétition riche en leucine
  • Récepteurs analogues à NOD
  • Récepteurs semblables à NOD
  • Récepteurs similaires à NOD

URI

http://data.loterre.fr/ark:/67375/JVR-MQRWZGD9-T

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