Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor

Preferred term

Maturation-Promoting Factor  

Type

  • mesh:Descriptor

Definition

  • Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Histone H1 Kinase, Growth-Associated
  • Histone H1 Kinase, M-Phase-Specific
  • Mitosis-Promoting Factor
  • M Phase-Promoting Factor

Allowable Qualifier(s)

In other languages

  • Facteur de promotion de la maturation

    French

  • Facteur de promotion de la mitose
  • Facteur de promotion de la phase M
  • Facteur MPF
  • Kinase de l'histone H1 associée à la croissance
  • Kinase de l'histone H1 spécifique de la phase M
  • Maturation-promoting factor
  • MPF (Maturation-Promoting Factor)

URI

http://data.loterre.fr/ark:/67375/JVR-MRBZ44KM-J

Download this concept:

RDF/XML TURTLE JSON-LD Created 6/17/90, last modified 5/21/21