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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains

Preferred term

Immunoglobulin J-Chains  

Type

  • mesh:Descriptor

Definition

  • A 15 kDa "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.

Broader concept

Related concepts

Entry terms

  • Ig J Chains
  • Ig J-Peptide
  • Immunoglobulin J-Peptide
  • Immunoglobulin J Polypeptide
  • J-Chains, Immunoglobulin

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Chaines J des immunoglobulines

    French

  • Chaines de jonction des Ig
  • Chaines de jonction des immunoglobulines
  • Chaines J d'immunoglobulines
  • Chaînes J des immunoglobulines
  • Peptide J
  • Pièce intermédiaire J

URI

http://data.loterre.fr/ark:/67375/JVR-MTRMC5NG-C

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