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Biological Factors > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Vascular Endothelial Growth Factor A
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Vascular Endothelial Growth Factor A
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Vascular Endothelial Growth Factors > Vascular Endothelial Growth Factor A

Preferred term

Vascular Endothelial Growth Factor A  

Type

  • mesh:Descriptor

Definition

  • The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.

Broader concept

Related concepts

Entry terms

  • Vascular Endothelial Growth Factor
  • Vascular Endothelial Growth Factor-A
  • Vascular Permeability Factor
  • Vasculotropin
  • VEGF
  • VEGF-A

Allowable Qualifier(s)

In other languages

  • Facteur de croissance endothéliale vasculaire de type A

    French

  • Facteur de croissance de l'endothélium vasculaire
  • Facteur de croissance de l'endothélium vasculaire A
  • Facteur de croissance de l'endothélium vasculaire de type A
  • Facteur de croissance endothéliale vasculaire
  • Facteur de croissance endothéliale vasculaire A
  • Facteur de perméabilité vasculaire
  • Vasculotropine
  • VEGF
  • VEGF-A

URI

http://data.loterre.fr/ark:/67375/JVR-MTSZTR5M-K

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RDF/XML TURTLE JSON-LD Created 7/9/03, last modified 7/9/13