Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Preferred term
Proto-Oncogene Proteins c-akt
Type
-
mesh:Descriptor
Definition
- Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
Broader concept
Entry terms
- akt Proto-Oncogene Protein
- c-akt Protein
- c-akt Proto-Oncogene Protein
- Protein Kinase B
- Protein-Serine-Threonine Kinase (Rac)
- Proto-Oncogene Protein Akt
- Proto-Oncogene Protein RAC
- RAC-PK Protein
- Rac Protein Kinase
- Related to A and C-Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéine c-akt
-
Protéine du proto-oncogène akt
-
Protéine du proto-oncogène c-akt
-
Protéine kinase B
-
Protéine kinase Rac
-
Protéine proto-oncogène Akt
-
Protéine proto-oncogène RAC
-
Protéine RAC-PK
-
Protéine sérine-thréonine kinase (Rac)
-
RAC (Related to A and C-protein)
-
Related to A and C-protein
URI
http://data.loterre.fr/ark:/67375/JVR-MTXXNHND-1
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