Concept information
Preferred term
Spheroids, Cellular
Type
-
mesh:Descriptor
Definition
- Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)
Broader concept
Entry terms
- Multicellular Spheroids
Allowable Qualifier(s)
- chemistry (Qualifier)
- classification (Qualifier)
- cytology (Qualifier)
- drug effects (Qualifier)
- enzymology (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- transplantation (Qualifier)
- ultrastructure (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Sphéroïdes cellulaires
-
Sphéroïdes multicellulaires
URI
http://data.loterre.fr/ark:/67375/JVR-MV01PJ81-B
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