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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Protein Interaction Domains and Motifs > Death Domain Superfamily > Pyrin Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Protein Interaction Domains and Motifs > Death Domain Superfamily > Pyrin Domain

Preferred term

Pyrin Domain  

Type

  • mesh:Descriptor

Definition

  • A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.

Broader concept

Related concepts

Entry terms

  • DAPIN Domain
  • PAAD-DAPIN-PYRIN Domain
  • PADD Domain
  • PYD Domain

Allowable Qualifier(s)

In other languages

  • Domaine pyrine

    French

  • Domaine DAPIN
  • Domaine PAAD-DAPIN-PYRIN
  • Domaine PADD
  • Domaine PYD

URI

http://data.loterre.fr/ark:/67375/JVR-MXPDHZG8-W

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/9/16