Concept information
Preferred term
Pro-Opiomelanocortin
Type
-
mesh:Descriptor
Definition
- A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Broader concept
Narrower concepts
Entry terms
- 66796-54-1
- 76775-14-9
- 78321-08-1
- ACTH-beta-Lipotropin Precursor
- ACTH-Endorphin Precursor
- Corticotropin-beta-Lipotropin Precursor
- Endorphin-ACTH Precursor
- Opiomelanocortin, pro-
- POMC
- Pro-ACTH-Endorphin
- Pro-Opiocortin
- Proopiocortin
- Pro-Opio-Melanocortin
- Proopiomelanocortin
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
66796-54-1
-
76775-14-9
-
78321-08-1
-
Opiomelanocortin, pro-
-
POMC
-
Pro-opio-mélanocortine
-
Pro-opiocortine
-
Proopiocortine
-
Proopiomélanocortine
URI
http://data.loterre.fr/ark:/67375/JVR-N10G7KH2-6
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