Concept information
Preferred term
BRCA2 Protein
Type
-
mesh:Descriptor
Definition
- A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
Broader concept
Entry terms
- BRCA2 Gene Product
- Breast Cancer 2 Gene Product
- Breast Cancer 2 Protein
- FANCD1 Protein
- Fanconi Anemia Complementation Group D1 Protein
- Fanconi Anemia Group D1 Complementing Protein
- Fanconi Anemia Group D1 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Produit du gène BRCA2
-
Produit du gène-2 du cancer du sein
-
Protéine du groupe D1 de l'anémie de Fanconi
-
Protéine du groupe de complémentation D1 de l'anémie de Fanconi
-
Protéine FANCD1
-
Protéine-2 du cancer du sein
URI
http://data.loterre.fr/ark:/67375/JVR-N42CZ2ZK-4
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