Concept information
Preferred term
Secologanin Tryptamine Alkaloids
Type
-
mesh:Descriptor
Definition
- Compounds formed by condensation of secologanin with tryptamine resulting in a tetrahydro-beta-carboline which is processed further to a number of bioactive compounds. These are especially found in plants of the APOCYNACEAE; LOGANIACEAE; and RUBIACEAE families. An alkaloidal extract from RAUWOLFIA. Alkaloids from Rauwolfia serpentina Benth and other species. The prototype is RESERPINE, which is a depleter of catecholamines and serotonin from the sympathetic postganglionic fibers and brain areas. They have been used in hypertension and psychoses despite their wide range of potentially adverse effects.
Broader concept
Narrower concepts
Entry terms
- Monoterpenoid Indole Alkaloids
- Secologanin Indole Alkaloids
- Strictosidine Derivatives
- Terpenoid Indole Alkaloids
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Alcaloïdes dérivés de sécologanine et tryptamine
-
Alcaloïdes indoliques monoterpéniques
-
Alcaloïdes indoliques terpéniques
URI
http://data.loterre.fr/ark:/67375/JVR-N6CQML7N-T
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