Concept information
Preferred term
Hemidesmosomes
Type
-
mesh:Descriptor
Definition
- An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS.
Broader concept
Allowable Qualifier(s)
- chemistry (Qualifier)
- classification (Qualifier)
- drug effects (Qualifier)
- enzymology (Qualifier)
- genetics (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- transplantation (Qualifier)
- ultrastructure (Qualifier)
- virology (Qualifier)
In other languages
-
French
URI
http://data.loterre.fr/ark:/67375/JVR-NB2T2L4H-Q
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