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Concept information

Preferred term

Soluble Guanylyl Cyclase  

Type

  • mesh:Descriptor

Definition

  • A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.

Broader concept

Entry terms

  • Nitric Oxide Receptor
  • Nitric Oxide Receptors
  • Nitric Oxide-Sensitive Guanylyl Cyclase
  • Receptor, Nitric Oxide
  • Soluble Guanylate Cyclase

In other languages

  • French

  • Guanylyl cyclase sensible au monoxyde d'azote
  • Guanylyl cyclase soluble
  • Récepteur du monoxyde d'azote
  • Récepteurs du monoxyde d'azote

URI

http://data.loterre.fr/ark:/67375/JVR-NJ40XPFW-7

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