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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase

Preferred term

Steroid 21-Hydroxylase  

Type

  • mesh:Descriptor

Definition

  • An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

Broader concept

Related concepts

Entry terms

  • 21-Hydroxylase
  • Cytochrome P-450 21-Hydroxylase
  • Cytochrome P-450 c21
  • Cytochrome P-450(c-21)
  • Cytochrome P450c21
  • Cytochrome P-450 CYP21
  • Progesterone 21-Hydroxylase
  • Steroid-21-Hydroxylase
  • Steroid 21-Monooxygenase
  • Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)

Allowable Qualifier(s)

In other languages

  • Steroid 21-hydroxylase

    French

  • 21-Hydroxylase
  • CYP 21
  • CYP21
  • Cytochrome P-450 CYP21
  • Cytochrome P450 21
  • Cytochrome P450c21
  • Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)
  • Stéroïde 21-hydroxylase
  • Stéroïde 21-monooxygénase

URI

http://data.loterre.fr/ark:/67375/JVR-NMVT6C53-1

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RDF/XML TURTLE JSON-LD Created 4/15/77, last modified 6/1/16