Concept information
Preferred term
Meglutol
Type
-
mesh:Descriptor
Definition
- An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Broader concept
Entry terms
- 3-Hydroxy-3-methylglutaric Acid
- 3-Hydroxy-3-methylpentanedioic Acid
- 503-49-1 (Meglutol)
- beta-Hydroxy-beta-Methylglutarate
- CLA99KCD53
- Pentanedioic acid, 3-hydroxy-3-methyl-
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
503-49-1 (Meglutol)
-
Acide 3-hydroxy-3-méthyl-glutarique
-
Acide 3-hydroxy-3-méthylglutarique
-
CLA99KCD53
-
Pentanedioic acid, 3-hydroxy-3-methyl-
URI
http://data.loterre.fr/ark:/67375/JVR-NRDW83SX-0
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