: MeSH: Alternative Splicing

Metabolism > RNA Processing, Post-Transcriptional > RNA Splicing > Alternative Splicing

Chemical Phenomena > Biochemical Phenomena > RNA Processing, Post-Transcriptional > RNA Splicing > Alternative Splicing

Genetic Phenomena > Gene Expression Regulation > RNA Processing, Post-Transcriptional > RNA Splicing > Alternative Splicing

Alternative Splicing

A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different. Alternatively spliced RNA transcripts that are derived from a set of exons that are located in the middle of the primary transcript (RNA PRECURSORS), between unused exons.

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