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... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Ion Channels > Ligand-Gated Ion Channels > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Ion Channels > Ligand-Gated Ion Channels > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Ion Channels > Ligand-Gated Ion Channels > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Channels > Ligand-Gated Ion Channels > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Channels > Ligand-Gated Ion Channels > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Neurotransmitter > Receptors, Amino Acid > Receptors, Glutamate > Receptors, Ionotropic Glutamate > Receptors, N-Methyl-D-Aspartate

Preferred term

Receptors, N-Methyl-D-Aspartate  

Type

  • mesh:Descriptor

Definition

  • A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.

Broader concept

Related concepts

Entry terms

  • NMDA Receptor
  • NMDA Receptor-Ionophore Complex
  • NMDA Receptors
  • N-Methylaspartate Receptors
  • N-Methyl-D-Aspartate Receptor
  • N-Methyl-D-Aspartate Receptors
  • Receptors, NMDA
  • Receptors, N-Methylaspartate

Allowable Qualifier(s)

In other languages

  • Récepteurs du N-méthyl-D-aspartate

    French

  • Complexe ionophore-récepteur du NMDA
  • Récepteurs au N-méthyl-D-aspartate
  • Récepteurs au NMDA
  • Récepteurs de N-méthyl-D-aspartate
  • Récepteurs du NMDA
  • Récepteurs glutaminergiques de type NMDA
  • Récepteurs NMDA

URI

http://data.loterre.fr/ark:/67375/JVR-NVMV5JBK-N

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RDF/XML TURTLE JSON-LD Created 5/31/90, last modified 5/27/20