Concept information
Preferred term
Receptors, KIR
Type
-
mesh:Descriptor
Definition
- A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
Broader concept
Narrower concepts
Entry terms
- Killer Cell Immunoglobulin-Like Receptor
- Killer Cell Immunoglobulin-Like Receptors
- Killer Immunoglobulin-Like Receptor
- Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors
- Killer Inhibitory Receptor
- Killer Inhibitory Receptors
- KIR Family Receptors
- KIR Receptor
- KIR Receptors
- p58 Natural Killer Cell Receptor
- p58 NK Cell Inhibitory Receptor
- p58 NK Cell Receptor
- p58 NK Cell Receptors
- Receptor, Killer Inhibitory
- Receptor, p58 NK Cell
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
-
French
-
Famille des récepteurs KIR
-
Récepteur KIR
-
Récepteurs de cellules NK de type immunoglobuline
-
Récepteurs de type immunoglobuline des cellules NK
-
Récepteurs des cellules NK p58
-
Récepteurs inhibiteurs des cellules K
-
Récepteurs inhibiteurs des cellules NK
-
Récepteurs NK
URI
http://data.loterre.fr/ark:/67375/JVR-NVT4SSXR-W
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