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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Diester Hydrolases > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3

Preferred term

Cyclic Nucleotide Phosphodiesterases, Type 3  

Type

  • mesh:Descriptor

Definition

  • A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing.

Broader concept

Entry terms

  • cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase
  • cGMP-Inhibited Phosphodiesterase
  • Cyclic Nucleotide Phosphodiesterase PDE3 Family
  • Phosphodiesterase III

Allowable Qualifier(s)

In other languages

  • Cyclic Nucleotide Phosphodiesterases, Type 3

    French

  • PDE inhibée par la GMPc de type 3
  • PDE-3 inhibée par la GMPc
  • PDE3 inhibée par la GMPc
  • Phosphodiestérase III
  • Phosphodiestérase inhibée par la GMP cyclique
  • Phosphodiestérase inhibée par la GMPc
  • Phosphodiestérase inhibée par le nucléotide cyclique GMPc
  • Phosphodiestérase-3
  • Phosphodiestérases des nucléotides cycliques de type 3
  • Phosphodiestérases des nucléotides cycliques de type III
  • Phosphodiestérases PDE3

URI

http://data.loterre.fr/ark:/67375/JVR-P2BS6TB8-H

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