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... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies

Preferred term

Promyelocytic Leukemia Nuclear Bodies  

Type

  • mesh:Descriptor

Definition

  • Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.

Broader concept

Entry terms

  • PML Bodies
  • PML NBs
  • PML Nuclear Bodies
  • Promyelocytic Leukemia Nuclear Body
  • Promyelocytic Leukemia Protein Bodies
  • Promyelocytic Leukemia Protein Body

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-P43Q3SK5-S

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RDF/XML TURTLE JSON-LD Created 7/9/21, last modified 7/1/21