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Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microfilament Proteins > Filamins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Filamins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Filamins
Macromolecular Substances > Polymers > Biopolymers > Microfilament Proteins > Filamins
... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins
Amino Acids, Peptides, and Proteins > Proteins > Contractile Proteins > Filamins

Preferred term

Filamins  

Type

  • mesh:Descriptor

Definition

  • A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.

Broader concept

Entry terms

  • Filamin

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-P449VH1K-N

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RDF/XML TURTLE JSON-LD Created 7/8/13, last modified 6/28/16