Concept information
Preferred term
Bromouracil
Type
-
mesh:Descriptor
Definition
- 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
Broader concept
Entry terms
- 2,4(1H,3H)-Pyrimidinedione, 5-bromo-
- 4HK400G5UO
- 51-20-7 (Bromouracil)
- 5-Bromouracil
- Bromuracil
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
2,4(1H,3H)-Pyrimidinedione, 5-bromo-
-
4HK400G5UO
-
5-Bromo-uracile
-
5-Bromouracile
-
51-20-7 (Bromouracil)
-
Bromouracile
URI
http://data.loterre.fr/ark:/67375/JVR-P69BPHTG-D
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